The synthetic evaluation based on the exploratory factor analysis indicated that the foreign trade development in Chinese mainland presents the unbalanced situation:eastern area heads the list and northeastern, mid-west areas decreases gradually.During 1985-2006, the difference of foreign trade quantity between four major regions increases step by step and the difference in internal regions tends restraining.In finished-product trade, eastern area occupies the national dominant position all the time and the ration rises year by year.In the forming process of foreign trade difference, factors such as open policy, foreign direct investment, human capital, economic infrastructure, domestic investment and geographical position play the decisive role.And the demonstration test which is carried on by the Log Unit Model indicates that expanding the road traffic construction, enhancing the decentralization level between central government and the local government, improving investment scale, increasing human capital condition, promoting communication level and strengthening the inter-provincial foreign trade cooperation, are the efficient paths to guide regional foreign trade development in the balanced direction.