By far almost natural resource assessments are single resource analyses. Though re-gional resource assessments seem to be comprehensive,these assessments can not fit into practices and left many problems to be solved by other remedial measures. For these rea-sons, the paper presents a new comprehensive natural resource assessment. The method is to analyse the entirety of combined natural resources including their sorts,quantities and qualities (grades) in a given region,to diagnose the combination,value construction of natural resources,and to put forward a series of developing orders,patterns and pro-cedures. The purposes are to avoid waste of resources,to prevent natural resources from being destroyed,and to help producers establish developing natural resource complex. Afterwards, the paper narrated the classificational principles (comprehensive,multiple developing and demarcation lines mainly coincidence),20 graphic relations of resources and regional conditions, 16 items and their indexes, as well as method, procedure and system of comprehensive natural resource assessment.