地理科学 ›› 1985, Vol. 5 ›› Issue (1): 30-37.doi: 10.13249/j.cnki.sgs.1985.01.30

• 论文 • 上一篇    下一篇

我国大骨节病的地理流行病学特点和环境病因研究

环境与地方病组   

  1. 中国科学院地理研究所
  • 出版日期:1985-01-20 发布日期:1985-01-20

THE CHARACTERISTICS OF GEOGRAPHICAL EPIDEMIOLOGY FOR KASCHIN-BECK’S DISEASE IN CHINA AND ITS PATHOGENICITY

The Group of Environment and Endemic Disease   

  1. Institute of Geography, Academia Sinica
  • Online:1985-01-20 Published:1985-01-20

摘要: 大骨节病是一种病因不明的地方性、多发性骨关节病。临床表现为关节疼痛、增粗、变形、运动障碍,肌肉萎缩,重者肢体矮小畸形。分布在我国14个省(区)约290多个县境内,严重威胁和损害病区人民健康。此病在苏联、朝鲜和日本均有报导。

Abstract: This paper elucidated the characteristics of geographical epidemiology from the angle of disease ecology. Among them the apparent endemic distribution is the most important charaeteristics. It shows that the disease is closely related to natural environment. Obviously, there exists a KaschinBeck’s disease belt and two non-disease belts in China. According to the natural features of disease-areas, eight envromental groups of diseae-areas can be divided and respectively were merged into three types. The main feature of chemical geography in Kaschin-Beck’s disease area is just like that in Keshan disease area, selenium content in environment in the affected areas is always lower. Hence, the two diseases often emege simultaneously in many cases, but Sometimes in some areas, such as in the area with lower selenium content, one of ths two occurs alone. In this paper, the authors made an approach to disese-cause of Kaschin-Beck’s disease. The low selenium content in environment is a basic factor in appearence of Kaschin-Beck’s disease, but some other factors must be taken into account. All of factors was called compound factors. The other factors include (1) Vitamins, for example Ve, (2) Some life elements related with selenium, such as Cd, Hg, Ag, Mo. Fe, Sr, Zn, etc.,(3)Some organic matter or some toxins in affected areas,(4) Some habits.