Abstract: In this paper,the series of the winter temperature departure in the east China and the global temperature departure for the last 500 years are analysed,and the fluctuation of cold/warm is described. The regional division of drought/flood in China in cold and warm periods are discussed. There are two main demarcations between drought and flood in the east China. The first one is the demarcatoin between more drought and more flood area. In the east China,the more drought area includes three regions in the north. The other is the more flood area. which includes other regions in the south. The second one is the mark to make out which area has the more occurrences of drought and flood or which has the less ones,which lies to the south of the fist demarcation,divides the flood and drought ares of southern China into two categores in terms of the multi-flood-drought area which include three regions in the south to the Yangtze River. In the cold or warm period,the demarcation of flood and drought in the east China holds the marked differences. The areas of the largest changes stand in Shandong Province,northern part of Jiangsu Province, northern part of Anhui Province, and the lower reaches of the Yangtze River. Whereas, the demarcation lying to the west of 110癊 is not likely to move or change. The demarcations and the regions of drought/flood shifted to south in the cold period and moved to north during the warm period.