Abstract: Industry structure effect has been one of the important factors affecting regional economy increment. Especially the industry structure and its spatial distribution of central city play an important role for regional economy development. Research on these facets could provide reasons and grounds for adjustment and arrangement of industry structure. Changchun City is the central city of Jilin Province and belongs to a developing city. Its economy and society have made a great progress since the foundation of the People's Republic of China in 1949. However, the existing problems, especially the unreasonable industry structure, have already limited the further development of the city. This paper summarized city's features and law of distribution of the industry structure to provide solutions for rapid development of the economy with the analysis of the current situation of the industrial structure. By means of the investigation and data analysis, we described the current situation of Changchun city's social-economic development and the status of gathering and radiating. Through investigation of distribution of the three industrial structures, the study analyzed the influence of the distribution of the industrial structure on city's economy, and pointed out the direction for adjustment of industry structure in future. The further suggestions on rearrangement of industry structure of Changchun City are: (1) Gathering the auto factory, car factory and their matching companies to the southeast. If necessary, the auto factory can be portioned as a single administration zone separately for efficient management. (2) Dispersing the small enterprise engaging in the tertiary industry to the urban zone. At present, most service enterprises mustered in several big traditional commercial zones, such as Damalu road, railway station, Chongqing road, and Hongqi street etc. Along with the economy development, service industry have taken place an dispersive trend, especially nearbouring the Yatai square. (3) Adjusting the developing direction of the two development zone, i.e. Changchun Economic and Technological Development Zone and Changchun High Technology Development Zone. We can adopted some ways such as land replacement, to expand the Changchun Economic and Technological Development Zone to the Xinglongshan, and to stretch Changchun High Technology Development Zone to the Fufengzhen. In addition, we should place the industry projects at the sides of Chang-Ji(Changchun-Jilin) and Chang-Ping(Changchun-Siping) railways to form an belt distribution. (4) Transiting the enterprises with heavy pollution and big water consumption far from the main city zone. Some introduced projects should be placed at the water sources nearby. The Luyuan district should be constructed as the ecological and green urban zone to lessen the pollution from the windward. (5) Developing and constructing strivingly the important towns along the transportation lines such as Mishazi, Nong'an, etc. The size of the towns should be enlarged gradually to accelerate economy development.