Abstract: In this paper, classified quantitative analysis of changed runoff and sediment yields caused by changing climatic conditions and human activities within a basin was done by making use of physical conceptual model. It has been tested if it is efficient and rational for the flow-sediment coupled simulation model for middle large scale basin introduced in literature to apply to simulate flow-sediment of Jingcun basin and Hekou Longmen interarea, and the results were satisfactory. Quantitative analysis periods were divided according to the effects of changing human activities on basin flow-sediment yields. Methods of classified quantitative analysis were proposed, and quantities of changed flow-sediment yields caused by changing climatic conditions and human activities were analysiszed for various periods.